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#4 in Nootropics & Brain Health Third-Party Tested

Host Defense Lion's Mane Capsules

by Host Defense (Fungi Perfecti)

"Paul Stamets' legendary lion's mane for nerve and brain support"

Amazon Rating
4.4/5
Reviews
18,000+
Price Range
$22-28
Servings
60 capsules (30 servings)
USDA OrganicNon-GMO Project Verified
Our Editorial Rating
7.8
Good
FormCapsule
SubcategoryMushroom Supplement
View on Amazon

Overview

Host Defense Lion's Mane is created by Paul Stamets, the world's most famous mycologist and star of the documentary Fantastic Fungi. Each serving provides 1g of lion's mane mycelium grown on organic brown rice. Lion's mane (Hericium erinaceus) contains compounds called hericenones and erinacines that stimulate Nerve Growth Factor (NGF) production, supporting brain health and nerve regeneration. Host Defense uses a proprietary growing process and freeze-drying to preserve bioactive compounds.

Key Ingredients

IngredientAmount
Lion's Mane Mycelium1,000 mg
Freeze-dried mycelium biomassFull spectrum

Pros & Cons

What We Like

  • Created by Paul Stamets — world-renowned mycologist
  • Organic and sustainably grown in the USA
  • Full-spectrum mycelium with bioactive compounds
  • Supports NGF production for brain health
  • Certified Organic by USDA

What Could Be Better

  • Uses mycelium on grain (not fruiting body)
  • Controversial — some experts prefer fruiting body extracts
  • Only 30 servings per bottle
  • Contains rice starch from growing substrate

Who Is This For?

Best For

  • Paul Stamets fans
  • Those wanting organic mushroom supplements
  • Cognitive support seekers
  • Nerve health support

Not Ideal For

  • Those who prefer fruiting body extracts
  • Budget shoppers
  • Those wanting standardized beta-glucan content

Our Verdict

7.8/10 — Good

Host Defense Lion's Mane is the most recognizable mushroom supplement brand, backed by Paul Stamets' expertise. The mycelium-on-grain approach is debated in the mushroom supplement community, but the brand's commitment to organic growing and research is genuine.

Alternatives to Consider

No direct alternatives listed for this product yet.