Pure Encapsulations B-Complex Plus
by Pure Encapsulations
"Practitioner-grade B-complex with active forms — methylfolate, methylcobalamin, and P5P in hypoallergenic formula"
Overview
Pure Encapsulations B-Complex Plus provides all eight B vitamins in their active, coenzyme forms: methylfolate (not folic acid), methylcobalamin (not cyanocobalamin), pyridoxal-5-phosphate (not pyridoxine), riboflavin-5-phosphate (not riboflavin), and benfotiamine (not thiamine). These active forms don't require conversion in the body, making them immediately bioavailable — especially important for those with MTHFR polymorphisms or other methylation issues. The hypoallergenic formulation contains no fillers, allergens, or excipients.
Key Ingredients
| Ingredient | Amount |
|---|---|
| Methylfolate (5-MTHF) | 400 mcg DFE |
| Methylcobalamin (Active B12) | 400 mcg |
| Pyridoxal-5-Phosphate (Active B6) | 16.5 mg |
| Benfotiamine (Active B1) | Included |
| Riboflavin-5-Phosphate (Active B2) | Included |
Pros & Cons
What We Like
- All active/coenzyme B vitamin forms
- MTHFR-friendly (methylfolate + methylcobalamin)
- Hypoallergenic formulation
- Practitioner-grade quality
- 8,000+ Amazon reviews
What Could Be Better
- Premium price ($22-28)
- Only 60 capsules
- Moderate doses (not high-potency)
- Most expensive B-complex per capsule
Who Is This For?
Best For
- MTHFR mutation carriers
- Those wanting active B vitamin forms
- Practitioner-recommended B-complex
- Sensitive individuals (hypoallergenic)
Not Ideal For
- Budget B-complex seekers
- Those wanting high-potency doses
- Those without methylation concerns
Our Verdict
Pure Encapsulations B-Complex Plus is the practitioner-grade B-complex for those who need active vitamin forms. The methylfolate and methylcobalamin are essential for MTHFR carriers, and the hypoallergenic formulation is safe for the most sensitive individuals.